Dr. Miles Neale offers us his breadth of knowledge about psychology, Buddhism, suffering, and psychedelics. We begin this conversation with Miles describing his early training, teachers, and practice as he traces the path of his development as a psychotherapist and teacher of Buddhism. Dr. Neale emphasizes a multidisciplinary dialogic process that is necessary to address the suffering of our time. We discuss The Four Noble Truths, a foundational insight and scaffolding of Buddhism, and use this frame to describe the problem, the cause of the problem, the potential for a solution, and the path for the solution, we explore materialism as a worldview that is the problem, define materialism and nihilism, the limitations and value of materialism and the overwhelming reliance on the scientific worldview – to the exclusion of religion, Tibetan history and practice, oracles, the confluence between easter and wester traditions, the Holy Grail, the Jungian Self and Buddhist no self, metaphysics, a spiritual path, the Three Jewels, and more.